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Ferritin Light Chain antibody [FTL/1388]

Anti-Ferritin Light Chain antibody [FTL/1388] used in Western Blot (WB). GTX34723
Anti-Ferritin Light Chain antibody [FTL/1388] used in Western Blot (WB). GTX34723
Anti-Ferritin Light Chain antibody [FTL/1388] used in IHC (Paraffin sections) (IHC-P). GTX34723
Anti-Ferritin Light Chain antibody [FTL/1388] used in IHC (Paraffin sections) (IHC-P). GTX34723
Anti-Ferritin Light Chain antibody [FTL/1388] used in Protein Array (Protein Array). GTX34723

Cat No. GTX34723

Host

Mouse

Clonality

Monoclonal

Clone Name

FTL/1388

Isotype

IgG2a

Application

WB, IHC-P, Protein Array

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2μg/ml
IHC-P 0.1-0.2μg/ml for 30 min at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

20 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

FTL , LFTD , NBIA3 , ferritin light chain , Ferritin Light Chain

Background

This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ferritin Light Chain antibody [FTL/1388] used in Western Blot (WB). GTX34723

GTX34723 WB Image

WB analysis of HeLa cell lysate using GTX34723 Ferritin Light Chain antibody [FTL/1388].

Anti-Ferritin Light Chain antibody [FTL/1388] used in Western Blot (WB). GTX34723

GTX34723 WB Image

WB analysis of human kidney tissue lysate using GTX34723 Ferritin Light Chain antibody [FTL/1388].

Anti-Ferritin Light Chain antibody [FTL/1388] used in IHC (Paraffin sections) (IHC-P). GTX34723

GTX34723 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX34723 Ferritin Light Chain antibody [FTL/1388].

Anti-Ferritin Light Chain antibody [FTL/1388] used in IHC (Paraffin sections) (IHC-P). GTX34723

GTX34723 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX34723 Ferritin Light Chain antibody [FTL/1388].

Anti-Ferritin Light Chain antibody [FTL/1388] used in Protein Array (Protein Array). GTX34723

GTX34723 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1388). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf