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Fibrinogen antibody [27C8]

Cat No. GTX10067

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 27C8

Isotype

 IgG2a

Application

 WB, ELISA, sELISA

Reactivity

 Human
Package
100 μg ($239)
See all Fibrinogen products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
sELISA Assay dependent

Note :

sELISA
Capture : GTX10066, Detection : GTX10067
Not tested in other applications.

Calculated MW

94.97 kDa. ( Note )

Specificity/Sensitivity

fibrinogen and fibrin degradation products.

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fibrin degradation products.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

FGA, Fib2, fibrinogen alpha chain

Cellular Localization

Secreted

Background

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 239