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Fibrinogen beta antibody

Anti-Fibrinogen beta antibody used in Western Blot (WB). GTX54019

Cat. No. GTX54019

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse, Rat
Package
100 μl ($399)
See all Fibrinogen beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887834

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibrinogen beta chain , HEL-S-78p

Cellular Localization

Secreted

Background

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Database

Research Area

DATA IMAGES

Anti-Fibrinogen beta antibody used in Western Blot (WB). GTX54019

GTX54019 WB Image

WB analysis of various sample lysates using GTX54019 Fibrinogen beta antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Onodi Z et al. Front Physiol 2018; 9 : 1479 Isolation of High-Purity Extracellular Vesicles by the Combination of * Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.
Application : WB
Reactivity : Rat
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399