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Fibulin 5 antibody [1G6A4]

Anti-Fibulin 5 antibody [1G6A4] used in IHC (Paraffin sections) (IHC-P). GTX83040
Anti-Fibulin 5 antibody [1G6A4] used in Western Blot (WB). GTX83040

Cat. No. GTX83040

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1G6A4

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μl ($409)
See all Fibulin 5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibulin 5 , ADCL2 , ARCL1A , ARMD3 , DANCE , EVEC , FIBL-5 , HNARMD , UP50

Cellular Localization

Secreted

Background

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Fibulin 5 antibody [1G6A4] used in IHC (Paraffin sections) (IHC-P). GTX83040

GTX83040 IHC-P Image

IHC-P analysis of human colon cancer (left) and breast cancer (right) using GTX83040 Fibulin 5 antibody [1G6A4].

Anti-Fibulin 5 antibody [1G6A4] used in Western Blot (WB). GTX83040

GTX83040 WB Image

WB analysis of truncated Fibulin 5 (His tag) recombinant protein using GTX83040 Fibulin 5 antibody [1G6A4].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409