GeneTex

  • Country / Location Selection

United States (US)

Fibulin 5 antibody

Anti-Fibulin 5 antibody used in Western Blot (WB). GTX64424
Anti-Fibulin 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64424

Cat. No. GTX64424

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Fibulin 5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 199-448 of human FBLN5 (NP_006320.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibulin 5 , ADCL2 , ARCL1A , ARMD3 , DANCE , EVEC , FIBL-5 , HNARMD , UP50

Cellular Localization

Secreted

Background

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Fibulin 5 antibody used in Western Blot (WB). GTX64424

GTX64424 WB Image

WB analysis of various sample lysates using GTX64424 Fibulin 5 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Fibulin 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64424

GTX64424 ICC/IF Image

ICC/IF analysis of L929 cells using GTX64424 Fibulin 5 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

There are currently no references for Fibulin 5 antibody (GTX64424). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Fibulin 5 antibody (GTX64424). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399