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Flt3 Ligand antibody

Cat No. GTX41115

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA, Functional Assay

Reactivity

Human
Package
100 μg ($459)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.2μg/ml
ELISA 0.5μg/ml
Functional Assay 0.25-0.75μg/ml
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Specificity/Sensitivity

This antibody may be used in an indirect ELISA system or as a capture antibody in a sandwich ELISA for human Flt3L in combination with GTX43881 as the detection antibody.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human Flt3-Ligand.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Fms Related Tyrosine Kinase 3 Ligand , Fl , Flg3L , Flt3L , Flt3Lg

Background

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 459