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Folate Receptor alpha antibody [BN3.2]

Anti-Folate Receptor alpha antibody [BN3.2] used in IHC (Paraffin sections) (IHC-P). GTX01976

Cat. No. GTX01976

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 BN3.2

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($609)
See all Folate Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections.
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to 189 amino acids of the external domain of the folate receptor alpha molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

folate receptor 1 , FBP , FOLR

Cellular Localization

Secreted , Cytoplasmic vesicle , Endosome , Apical cell membrane

Background

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Folate Receptor alpha antibody [BN3.2] used in IHC (Paraffin sections) (IHC-P). GTX01976

GTX01976 IHC-P Image

IHC-P analysis of ovarian tumor tissue using GTX01976 Folate Receptor alpha antibody [BN3.2]. Note intense cytoplasmic staining.

REFERENCE

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REVIEW

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Package List Price ($)
$ 609