GeneTex
  • Country / Location Selection

United States (US)

Folylpolyglutamate synthase antibody [N3C2], Internal

Anti-Folylpolyglutamate synthase antibody [N3C2], Internal used in Western Blot (WB). GTX103516

Cat No. GTX103516

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

65 kDa. ( Note )

Positive Control

Folylpolyglutamate synthase tansfected 293T cell

Predict Reactivity

Bovine(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Folylpolyglutamate synthase. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

folylpolyglutamate synthase

Cellular Localization

Mitochondrion , Cytoplasm

Background

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq]

Database

Research Area

DATA IMAGES
Anti-Folylpolyglutamate synthase antibody [N3C2], Internal used in Western Blot (WB). GTX103516

GTX103516 WB Image

Western Blot analysis of FPGS expression in transfected 293T cell line by FPGS polyclonal antibody.
A: Non-transfected lysate.
B: FPGS transfected lysate.
7.5% SDS PAGE
GTX103516 diluted at 1:1000

REFERENCE
REVIEW
There are currently no reviews for Folylpolyglutamate synthase antibody [N3C2], Internal (GTX103516). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169