GeneTex
United States (US)

Fos B antibody

GTX101809_40723_WB_M_19011506_292.jpg
GTX101809_40723_WB_19011506_918.jpg

Cat No. GTX101809

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

Positive Control

HeLa , NIH-3T3

Predict Reactivity

Rat, Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Fos B. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Fosb Proto-Oncogene, Ap-1 Transcription Factor Subunit,Ap-1,G0S3,Gos3,Gosb,Fosb

Cellular Localization

Nucleus

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX101809_40723_WB_M_19011506_292.jpg

GTX101809 WB Image

Sample (30 ug of whole cell lysate)
A: NIH-3T3
10% SDS PAGE
GTX101809 diluted at 1:1000

GTX101809_40723_WB_19011506_918.jpg

GTX101809 WB Image

Fos B antibody detects FOSB protein by Western blot analysis.
A. 30 µg HeLa whole cell lysate/extract
15 % SDS-PAGE
Fos B antibody (GTX101809) dilution: 1:1000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf