APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
1:1000 |
1:10-1:50 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.09% sodium azide.
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 72-102 amino acids from the Central region of human FXN.
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
frataxin , CyaY , FA , FARR , FRDA , X25
Cellular Localization
Mitochondrion,Cytoplasm, cytosol
Background
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Database
Research Area
DATA IMAGES
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GTX81888 ICC/IF Image
ICC/IF analysis of WiDr cells using GTX81888 Frataxin antibody, Internal. Green : Frataxin Blue : DAPI
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GTX81888 WB Image
WB analysis of CEM cell lysate (35ug/lane) using GTX81888 Frataxin antibody, Internal.
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GTX81888 IHC-P Image
IHC-P analysis of human colon carcinoma using GTX81888 Frataxin antibody, Internal.
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REFERENCE
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REVIEW
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