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Frizzled 4 antibody

Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992
Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992
Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992

Cat. No. GTX12992

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Chicken, Pig, Monkey, Bat, Horse
Package
25 μg ($399)
See all Frizzled 4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 25 μg/ml
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Predict Reactivity

Elephant, Gibbon, Lizard, Marmoset, Opossum, Panda, Turkey, Xenopus, Platypus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 13 amino acid peptide from C-terminus of human FZD4 / Frizzled 4.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

frizzled class receptor 4 , CD344 , EVR1 , FEVR , FZD4 , FZD4S , Fz4 , FzE4 , GPCR , hFz4 , Frizzled 4

Cellular Localization

Membrane,Cell membrane

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992

GTX12992 IHC-P Image

IHC-P analysis of human kidney tissue using GTX12992 Frizzled 4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992

GTX12992 IHC-P Image

IHC-P analysis of human pancreas, carcinoma tissue using GTX12992 Frizzled 4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX12992

GTX12992 IHC-P Image

IHC-P analysis of human skin, melanoma tissue using GTX12992 Frizzled 4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399