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Frizzled 6 antibody

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71521
Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71521

Cat No. GTX71521

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 14 μg/ml
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Predict Reactivity

Rabbit, Bovine, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Orangutan, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

frizzled class receptor 6 , FZ6 , FZD6 , HFZ6 , NDNC10 , Frizzled 6

Cellular Localization

Membrane,Cell membrane,Cell surface,Apical cell membrane,Cytoplasmic vesicle membrane

Background

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71521

GTX71521 IHC-P Image

IHC-P analysis of human liver tissue using GTX71521 Frizzled 6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 14 μg/ml

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71521

GTX71521 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX71521 Frizzled 6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 14 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 269