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Frizzled 6 antibody

Anti-Frizzled 6 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX71523
Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523
Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523
Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523

Cat No. GTX71523

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P

Reactivity

Human, Monkey
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 3 - 6 μg/ml
IHC-P 6 - 14 μg/ml
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Dog, Chicken, Pig, Bat, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Orangutan, Panda, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

frizzled class receptor 6 , FZ6 , FZD6 , HFZ6 , NDNC10 , Frizzled 6

Cellular Localization

Membrane,Cell membrane,Cell surface,Apical cell membrane,Cytoplasmic vesicle membrane

Background

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Frizzled 6 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX71523

GTX71523 ICC/IF Image

ICC/IF analysis of HEK293 transfected with Frizzled 6 using GTX71523 Frizzled 6 antibody.

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523

GTX71523 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX71523 Frizzled 6 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523

GTX71523 IHC-P Image

IHC-P analysis of human skin, melanoma tissue using GTX71523 Frizzled 6 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX71523

GTX71523 IHC-P Image

IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX71523 Frizzled 6 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

There are currently no references for Frizzled 6 antibody (GTX71523). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Frizzled 6 antibody (GTX71523). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 269