APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 20 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Rabbit, Dog, Hamster, Monkey, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human FZD7 / Frizzled 7.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375809
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
frizzled class receptor 7 , FZD7 , FzE3
Cellular Localization
Cell membrane,Endosome membrane
Background
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX71555 IHC-P Image
IHC-P analysis of human heart, cardiac myocytes tissue using GTX71555 Frizzled 7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71555 IHC-P Image
IHC-P analysis of human prostate, carcinoma tissue using GTX71555 Frizzled 7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71555 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX71555 Frizzled 7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71555 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX71555 Frizzled 7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
There are currently no reviews for Frizzled 7 antibody (GTX71555). Be the first to share your experience with this product.
