APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 30 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Marmoset, Opossum, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375801
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
frizzled class receptor 8 , FZ8 , FZD8 , hFZ8 , frizzled8
Cellular Localization
Membrane,Golgi apparatus,Cell membrane
Background
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX71543 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX71543 IHC-P Image
IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX71543 IHC-P Image
IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX71543 IHC-P Image
IHC-P analysis of human pancreas, islet of langerhans tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
REFERENCE
There are currently no references for Frizzled 8 antibody (GTX71543). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Frizzled 8 antibody (GTX71543). Be the first to share your experience with this product.
