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Frizzled 8 antibody

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

Cat No. GTX71543

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse, Rat, Monkey
Package
25 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 30 μg/ml
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

Predict Reactivity

Marmoset, Opossum, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

frizzled class receptor 8 , FZ8 , FZD8 , hFZ8 , frizzled8

Cellular Localization

Membrane,Golgi apparatus,Cell membrane

Background

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human pancreas, islet of langerhans tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human ovary, carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf