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Frizzled 8 antibody

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543
Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

Cat. No. GTX71543

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat, Monkey
Package
25 μg ($399)
See all Frizzled 8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 30 μg/ml
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

Predict Reactivity

Marmoset, Opossum, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_375801

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

frizzled class receptor 8 , FZ8 , FZD8 , hFZ8 , frizzled8

Cellular Localization

Membrane,Golgi apparatus,Cell membrane

Background

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human ovary, carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-Frizzled 8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71543

GTX71543 IHC-P Image

IHC-P analysis of human pancreas, islet of langerhans tissue using GTX71543 Frizzled 8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399