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G6PC antibody, N-term

Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748
Anti-G6PC antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46748
Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

Cat No. GTX46748

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

human fetal lung , MCF-7

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and may contain up to 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human G6PC

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11172680

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glucose-6-phosphatase catalytic subunit , G6PC1 , G6PT , G6Pase , GSD1 , GSD1a

Background

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

GTX46748 WB Image

WB analysis of human fetal lung tissue using GTX46748 G6PC antibody at 1μg/ml.

Anti-G6PC antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46748

GTX46748 IHC-P Image

IHC-P analysis of human kidney tissue using GTX46748 G6PC antibody at 5μg/ml.

Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

GTX46748 WB Image

WB analysis of MCF-7 cells using GTX46748 G6PC antibody at 1μg/ml.

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf