GeneTex
United States (US)

G6PC antibody, N-term

GTX46748_1487_WB_18121410_272.jpg
GTX46748_1486_IHC-P_18121410_665.jpg
GTX46748_1489_WB_18121410_944.jpg

Cat No. GTX46748

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

human fetal lung , MCF-7

Predict Reactivity

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 93%; Sheep: 100%
PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and may contain up to 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human G6PC

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glucose-6-Phosphatase Catalytic Subunit,G6Pc1,G6Pt,G6Pase,Gsd1,Gsd1A,G6Pc

Background

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES
GTX46748_1487_WB_18121410_272.jpg

GTX46748 WB Image

WB analysis of human fetal lung tissue using GTX46748 G6PC antibody at 1μg/ml.

GTX46748_1486_IHC-P_18121410_665.jpg

GTX46748 IHC-P Image

IHC-P analysis of human kidney tissue using GTX46748 G6PC antibody at 5μg/ml.

GTX46748_1489_WB_18121410_944.jpg

GTX46748 WB Image

WB analysis of MCF-7 cells using GTX46748 G6PC antibody at 1μg/ml.

REFERENCE
Package List Price ($)
$ 339