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G72 antibody

Anti-G72 antibody used in IHC (Paraffin sections) (IHC-P). GTX117488
Anti-G72 antibody used in Western Blot (WB). GTX117488

Cat No. GTX117488

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($329),
25 μl ($169)
See all G72 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Positive Control

PC-3

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human G72. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11170323

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

D-amino acid oxidase activator , LG72 , SG72

Cellular Localization

Golgi apparatus

Background

This gene encodes a protein that is an activator of the FAD-dependent enzyme D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder, possibly due to decreased levels of D-serine and decreased NMDA receptor functioning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-G72 antibody used in IHC (Paraffin sections) (IHC-P). GTX117488

GTX117488 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human gastric cancer, using G72 antibody(GTX117488) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-G72 antibody used in Western Blot (WB). GTX117488

GTX117488 WB Image

Sample (30 ug of whole cell lysate)
A: PC-3
12% SDS PAGE
GTX117488 diluted at 1:1000

REFERENCE

Application Reference

Hwang CS et al. Biomark Med 2016; 10 (1) : 26908 Decreased level of serum autoantibody against LG72 is a biosignature of amyotrophic lateral sclerosis.
Reactivity : Human
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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 329
$ 169