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GABA A Receptor alpha 5 antibody [S415-24]

Anti-GABA A Receptor alpha 5 antibody [S415-24] used in Western Blot (WB). GTX17517
Anti-GABA A Receptor alpha 5 antibody [S415-24] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX17517

Cat. No. GTX17517

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 S415-24

Isotype

 IgG1

Application

 WB, ICC/IF, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all GABA A Receptor alpha 5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

Product Note

Detects ~55kDa. Does not cross-react with GABA-A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gamma-aminobutyric acid type A receptor alpha5 subunit

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GABA A Receptor alpha 5 antibody [S415-24] used in Western Blot (WB). GTX17517

GTX17517 WB Image

WB analysis of mouse brain tissue using GTX17517 GABA A Receptor alpha 5 antibody [S415-24].
Loading : 20 μg
Dilution : 1:1000

Anti-GABA A Receptor alpha 5 antibody [S415-24] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX17517

GTX17517 ICC/IF Image

ICC/IF analysis of SK-N-BE cells using GTX17517 GABA A Receptor alpha 5 antibody [S415-24].
Fixation: 4% Formaldehyde for 15 min at RT
Dilution : 1:100
Blue : DAPI n
Red : Phalloidin (F-Actin stain)
Green : GABA A Receptor Alpha 5 Antibody

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399