GeneTex
United States (US)

GABA A Receptor gamma 2 antibody, Internal

GTX88118_2518_WB_18122102_125.jpg

Cat No. GTX88118

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88118-PEP).

Specificity/Sensitivity

This antibody is expected to recognize all reported isoforms: NP_944494.1; NP_000807.2; NP_944493.2. Note the aa numbers used in the name are from NP_944494.1.

Predict Reactivity

Human, Bovine(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-NNATHLQERDE, from the internal region of the protein sequence according to NP_944494.1; NP_000807.2; NP_944493.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Gamma-Aminobutyric Acid Type A Receptor Gamma2 Subunit,Cae2,Eca2,Gefsp3,Gabrg2

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX88118_2518_WB_18122102_125.jpg

GTX88118 WB Image

WB analysis of mouse brain lysate using GTX88118 GABA A Receptor gamma 2 antibody, Internal.
Dilution : 2µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329