GeneTex
United States (US)

GABA B Receptor 1 antibody

GTX30215_1366_WB_18121410_489.jpg

Cat No. GTX30215

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
Not tested in other applications.

Calculated MW

108 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues 33-54 [PHLPRPHPRVPPHPSSERRAVY] of the GABABR1 subunit.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GABABR1 antibody , GABBR1-3 antibody , GB1 antibody , GPRC3A antibody

Cellular Localization

Cell membrane, Multi-pass membrane protein,Cell junction,synapse,postsynaptic cell membrane, Multi-pass membrane protein,Isoform 1E: Secreted

Background

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX30215_1366_WB_18121410_489.jpg

GTX30215 WB Image

WB analysis of brain tissue lysate using GTX30215 GABA B Receptor 1 antibody.
Dilution : 1:500

Package List Price ($)
$ 329