0.01M PBS pH7.4, 1% BSA, 15 mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
peptide corresponding to human GADD153/CHOP10 sequence (amino acids 153-169) with N-terminal lysine added, conjugated to keyhole limpet hemocyanin (KLH). The corresponding sequence in mouse and rat differs by 2 amino acids.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
DNA damage inducible transcript 3 , AltDDIT3 , C/EBPzeta , CEBPZ , CHOP , CHOP-10 , CHOP10 , GADD153
DDIT3 is a basic region leucine zipper transcription factor, devoid of DNA binding site. It is capable of heterodimerizing with members of the CCAAT/ enhancer binding protein (C/EBP) family of transcription factors. It is both an activating and a repressing factor that is markedly induced in response to many signals such as growth arrest, DNA damage, calcium ionophore, nutrient deprivation, hypoxia, hyperoxia, hyperosmosis, and endoplasmic reticulum stress.