GeneTex

  • Country / Location Selection

United States (US)

GAK antibody [9-13]

Anti-GAK antibody [9-13] used in IHC (Paraffin sections) (IHC-P). GTX00873
Anti-GAK antibody [9-13] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00873
Anti-GAK antibody [9-13] used in Western Blot (WB). GTX00873

Cat. No. GTX00873

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 9-13

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all GAK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF 1:50
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

143 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Recombinant rat GAK (kinase domain, 1-430)

Purification

Purified IgG
From culture supernant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin G associated kinase , DNAJ26 , DNAJC26 , GAK

Cellular Localization

Cytoplasm,Perinuclear region,Golgi apparatus,trans-Golgi network,Cell junction,Focal adhesion

Background

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Database

Research Area

DATA IMAGES

Anti-GAK antibody [9-13] used in IHC (Paraffin sections) (IHC-P). GTX00873

GTX00873 IHC-P Image

IHC-P analysis of human prostate cancer tissue section using GTX00873 GAK antibody [9-13]. It showed nuclear accumulation of GAK in cancer cells.
Dilution : 1:50

Anti-GAK antibody [9-13] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00873

GTX00873 ICC/IF Image

ICC/IF analysis of TIG-1 cells using GTX00873 GAK antibody [9-13].
Dilution : 1:50

Anti-GAK antibody [9-13] used in Western Blot (WB). GTX00873

GTX00873 WB Image

WB analysis of TIG-1 and PC-3 whole cell lysates using GTX00873 GAK antibody [9-13].
Dilution : 1:500

REFERENCE

There are currently no references for GAK antibody [9-13] (GTX00873). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for GAK antibody [9-13] (GTX00873). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 399