GeneTex
United States (US)

GAK antibody

GTX34383_20170112_WB_18121410_593.jpg

Cat No. GTX34383

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA, IHC
Reactivity Human, Mouse
See all GAK products
APPLICATION

Calculated MW

143 kDa. ( Note )

Specificity/Sensitivity

GAK Polyclonal Antibody detects endogenous levels of GAK protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from the N-terminal region of human GAK at AA range: 70-150.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cyclin G Associated Kinase,Dnaj26,Dnajc26,Gak

Background

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Database

Research Area

DATA IMAGES
GTX34383_20170112_WB_18121410_593.jpg

GTX34383 WB Image

Western Blot (WB) analysis of specific cells using GAK Polyclonal Antibody.
Package List Price ($)
$ 319