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GALR1 antibody [C2C3], C-term

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207
Anti-GALR1 antibody [C2C3], C-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX108207

Cat. No. GTX108207

Reference 7

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all GALR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 1:100-1:1000
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Predict Reactivity

Rat, Bovine, Chicken, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human GALR1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037044

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

galanin receptor 1 , GALNR , GALNR1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

Galanin receptor 1 antibody [C2C3], C-term detects galanin receptor 1 protein at membrane on human small intestine by immunohistochemical analysis.
Sample: Paraffin-embedded small intestine.
galanin receptor 1 antibody [C2C3], C-term (GTX108207) dilutio
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Front Endocrinol (Lausanne) in 2020.PMID: 32265844

Anti-GALR1 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX108207

GTX108207 IHC-P Image

The data was published in the journal Sci Rep in 2019. PMID: 31076613

Anti-GALR1 antibody [C2C3], C-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX108207

GTX108207 ICC/IF Image

The data was published in the journal Sci Rep in 2019. PMID: 31076613

REFERENCE

Application Reference

Kiezun J et al. Biomolecules 2022; 12 (12) Galanin Receptors (GALR1, GALR2, and GALR3) Immunoexpression in Enteric Plexuses of Colorectal Cancer Patients: Correlation with the Clinico-Pathological Parameters.
Application : IHC-P, IHC-Fr
Reactivity : Human
Jacek Kiezun et al. Int J Mol Sci 2022; 23 (7) Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients.
Application : IHC-P
Ma W et al. J Dent Res 2021; 100 (10) : 1144-1152 Successful Application of a Galanin-Coated Scaffold for Periodontal Regeneration.
Application : IHC-P
Reactivity : Mouse
Brunner SM et al. Sci Rep 2021; 11 (1) : 564 Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model.
Application : IHC-P
Reactivity : Human
Falkenstetter S et al. Front Endocrinol (Lausanne) 2020; 11 : 155 Galanin System in Human Glioma and Pituitary Adenoma.
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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169