*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
Mouse, Rat, Bovine, Pig, Chimpanzee(>80% identity)
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.84mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the C-terminus region of human GBA. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
GBA1 antibody, GCB antibody, GLUC antibody, GBA antibody, imiglucerase antibody, lysosomal glucocerebrosidase antibody, glucosylceramidase antibody, acid beta-glucosidase antibody, beta-glucocerebrosidase antibody, D-glucosyl-N-acylsphingosine glucohydrolase antibody, alglucerase antibody, "glucosidase, beta, acid antibody"
Lysosome membrane; Peripheral membrane protein; Lumenal side
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
GTX101267 WB Image
MCF-7 whole cell and membrane extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with GBA antibody [C1C3] (GTX101267) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX101267 WB Image
Sample(30 µg of whole cell lysate)
7.5% SDS PAGE
GTX101267 diluted at 1:500
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX101267 IHC-P Image
Immunohistochemical analysis of paraffin-embedded human lung cancer, using GBA(GTX101267) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX101267 ICC/IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using GBA(GTX101267) antibody at 1:100 dilution.