APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 0.5 - 1 μg/mL |
| 2.5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Skeletal Muscle Tissue Lysate
Product Note
This antibody is specific for NIPSNAP2 N-Terminus
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
GBAS antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human GBAS.The immunogen is located within the first 50 amino acids of GBAS.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
nipsnap homolog 2 , GBAS
Cellular Localization
Cytoplasm,Mitochondrion outer membrane
Background
The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Database
DATA IMAGES
|
GTX85361 IHC-P Image
IHC-P analysis of mouse skeletal muscle tissue using GTX85361 GBAS antibody.
Working concentration : 2.5 μg/ml
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GTX85361 WB Image
WB analysis of human skeletal muscle tissue lysate using GTX85361 GBAS antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml
|
REFERENCE
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REVIEW
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