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GDF6 antibody, C-term

Anti-GDF6 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81418
Anti-GDF6 antibody, C-term used in Western Blot (WB). GTX81418
Anti-GDF6 antibody, C-term used in Flow cytometry (FACS). GTX81418

Cat. No. GTX81418

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all GDF6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Predict Reactivity

Rat, Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 326-353 amino acids from the C-terminal region of human GDF6.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

growth differentiation factor 6 , BMP-13 , BMP13 , CDMP2 , KFM , KFS , KFS1 , KFSL , SGM1 , SYNS4

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-GDF6 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81418

GTX81418 IHC-P Image

IHC-P analysis of human brain tissue using GTX81418 GDF6 antibody, C-term.

Anti-GDF6 antibody, C-term used in Western Blot (WB). GTX81418

GTX81418 WB Image

WB analysis of mouse kidney tissue lysate (35ug/lane) using GTX81418 GDF6 antibody, C-term.

Anti-GDF6 antibody, C-term used in Flow cytometry (FACS). GTX81418

GTX81418 FACS Image

FACS analysis of 293 cells using GTX81418 GDF6 antibody, C-term.
Top histogram : negative control
Bottom histogram : 293 cells

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399