APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
HeLa , HepG2 , IHKE1 , NIH3T3
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a C-terminal region of Human GDI1
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
GDP dissociation inhibitor 1 , 1A , GDIL , MRX41 , MRX48 , OPHN2 , RABGD1A , RABGDIA , XAP-4
Cellular Localization
Cytoplasm
Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific cognitive disability. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX30781 WB Image
WB analysis of HepG2 cells using GTX30781 GDI1 antibody at 1.25μg/ml.
Lane A : marker
Lane B : HepG2 cells
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GTX30781 WB Image
WB analysis of human HeLa, mouse NIH3T3, and human IHKE1 cells using GTX30781 GDI1 antibody at 1:1000.
Lane1: HeLa lysate
Lane2: NIH3T3 lysate
Lane3: IHKE1 lysate
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REFERENCE
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REVIEW
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