APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 μg/mL |
1 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Lysate(GTX27918) , Human Liver Tissue Lysate , Human Kidney Tissue Lysate(GTX29995) , Human Spleen Tissue Lysate(GTX27921)
Product Note
GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
GFR alpha 1 antibody was raised against a 14 amino acid peptide near the center of human GFR alpha 1.The immunogen is located within amino acids 360 - 410 of GFR alpha 1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
GDNF family receptor alpha 1 , GDNFR , GDNFRA , GFR-ALPHA-1 , RET1L , RETL1 , TRNR1
Cellular Localization
Cell membrane
Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]
Database
Research Area
DATA IMAGES
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GTX11115 WB Image
WB analysis of crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S) using GTX11115 GDNF Receptor alpha 1 antibody. Working concentration : 1 μg/ml
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GTX11115 IHC-P Image
IHC-P analysis of human brain tissue using GTX11115 GDNF Receptor alpha 1 antibody. Working concentration : 2.5 μg/ml
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GTX11115 IHC-P Image
IHC-P analysis of human brain tissue using GTX11115 GDNF Receptor alpha 1 antibody. Working concentration : 1 μg/ml
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GTX11115 IHC-P Image
IHC-P analysis of human brain tissue using GTX11115 GDNF Receptor alpha 1 antibody. Red : Primary antibody Blue : DAPI Dilution : 20 μg/ml
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REFERENCE
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REVIEW
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