GeneTex

  • Country / Location Selection

United States (US)

GDNF Receptor alpha 1 antibody

Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146
Anti-GDNF Receptor alpha 1 antibody used in Western Blot (WB). GTX54146
Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146
Anti-GDNF Receptor alpha 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54146
Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146

Cat. No. GTX54146

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all GDNF Receptor alpha 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human GFRA1 (NP_665736.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

GDNF family receptor alpha 1 , GDNFR , GDNFRA , GFR-ALPHA-1 , RET1L , RETL1 , TRNR1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146

GTX54146 IHC-P Image

IHC-P analysis of human thyroid cancer tissue using GTX54146 GDNF Receptor alpha 1 antibody.
Dilution : 1:100

Anti-GDNF Receptor alpha 1 antibody used in Western Blot (WB). GTX54146

GTX54146 WB Image

WB analysis of various sample lysates using GTX54146 GDNF Receptor alpha 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146

GTX54146 IHC-P Image

IHC-P analysis of mouse testis tissue using GTX54146 GDNF Receptor alpha 1 antibody.
Dilution : 1:100

Anti-GDNF Receptor alpha 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54146

GTX54146 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX54146 GDNF Receptor alpha 1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-GDNF Receptor alpha 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54146

GTX54146 IHC-P Image

IHC-P analysis of rat testis tissue using GTX54146 GDNF Receptor alpha 1 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for GDNF Receptor alpha 1 antibody (GTX54146). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for GDNF Receptor alpha 1 antibody (GTX54146). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399