GeneTex
United States (US)

GDNF Receptor alpha 1 antibody

GTX54146_20180530_WB_18121410_345.jpg
GTX54146_20180530_ICCIF_18121410_549.jpg

Cat No. GTX54146

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

51 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 25-280 of human GFRA1 (NP_665736.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

RET1L Antibody , TRNR1 Antibody , GDNFR Antibody , GFR\ ALPHA1 Antibody , GFRA1 Antibody , GDNFRA Antibody , RETL1 Antibody

Background

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES
GTX54146_20180530_WB_18121410_345.jpg

GTX54146 WB Image

WB analysis of various samples using GTX54146 GDNF Receptor alpha 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX54146_20180530_ICCIF_18121410_549.jpg

GTX54146 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX54146 GDNF Receptor alpha 1 antibody.
Blue : DAPI

Package List Price ($)
$ 319