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GDNF Receptor alpha 2 antibody [11G34]

Cat No. GTX52762

Host

Mouse

Clonality

Monoclonal

Clone Name

11G34

Isotype

IgG2

Application

WB

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant GDNF-Rα2

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

GDNF family receptor alpha 2 , GDNFRB , GFRA2 , NRTNRALPHA , NTNRA , RETL2 , TRNR2 , GDNF Receptor alpha 2

Cellular Localization

Cell membrane

Background

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

REFERENCE

There are currently no references for GDNF Receptor alpha 2 antibody [11G34] (GTX52762). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for GDNF Receptor alpha 2 antibody [11G34] (GTX52762). Be the first to share your experience with this product.
SDS
PBS.pdf