Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
recombinant human GDNF expressed in Escherichia coli.
Purification
IgG fraction
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
glial cell derived neurotrophic factor , ATF , ATF1 , ATF2 , HFB1-GDNF , HSCR3
Cellular Localization
Secreted
Background
GDNF is a 20 kD glycosylated polypeptide that exists as a homodimer. The gene for GDNF has been mapped to human chromosome. There is significant sequence homology between rat and human GDNF. GDNF stimulates the growth of dopaminergic neurons and autonomic motor neurons. Recombinant GDNF is expressed in E. coli from a DNA sequence encoding the protein.
Database
Research Area