Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
recombinant human GDNF expressed in Escherichia coli.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Glial Cell Derived Neurotrophic Factor,Atf,Atf1,Atf2,Hfb1-Gdnf,Hscr3,Gdnf
GDNF is a 20 kD glycosylated polypeptide that exists as a homodimer. The gene for GDNF has been mapped to human chromosome. There is significant sequence homology between rat and human GDNF. GDNF stimulates the growth of dopaminergic neurons and autonomic motor neurons. Recombinant GDNF is expressed in E. coli from a DNA sequence encoding the protein.