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United States (US)

GDNF antibody

Cat. No. GTX10835

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

Neutralizing/Inhibition

Reactivity

Human
Package
200 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human GDNF expressed in Escherichia coli.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glial cell derived neurotrophic factor , ATF , ATF1 , ATF2 , HFB1-GDNF , HSCR3

Cellular Localization

Secreted

Background

GDNF is a 20 kD glycosylated polypeptide that exists as a homodimer. The gene for GDNF has been mapped to human chromosome. There is significant sequence homology between rat and human GDNF. GDNF stimulates the growth of dopaminergic neurons and autonomic motor neurons. Recombinant GDNF is expressed in E. coli from a DNA sequence encoding the protein.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399