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GGCX antibody, C-term

Anti-GGCX antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX88337
Anti-GGCX antibody, C-term used in Western Blot (WB). GTX88337

Cat No. GTX88337

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
IHC-P 5-10μg/ml

Note :

IHC-P
Human Kidney shows distinct staining in the cytoplasm of epthelial cells.

Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88337-PEP).

Product Note

This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).

Predict Reactivity

Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-PPESNPDPVHSE, from the C Terminus of the protein sequence according to NP_000812.2; NP_001135741.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

gamma-glutamyl carboxylase , VKCFD1

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Database

Research Area

DATA IMAGES

Anti-GGCX antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX88337

GTX88337 IHC-P Image

IHC-P analysis of human kidney using GTX88337 GGCX antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

Anti-GGCX antibody, C-term used in Western Blot (WB). GTX88337

GTX88337 WB Image

WB analysis of human muscle lysate using GTX88337 GGCX antibody, C-term.
Dilution : 0.3μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for GGCX antibody, C-term (GTX88337). Be the first to share your publications with this product.

REVIEW

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SDS
Sodium Azide.pdf