GeneTex
United States (US)

GGCX antibody, C-term

GTX88337_979_IHC-P_18121411_472.jpg
GTX88337_2372_WB_18121411_107.jpg

Cat No. GTX88337

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
IHC-P 5-10μg/ml

Note :

IHC-P
Human Kidney shows distinct staining in the cytoplasm of epthelial cells.

Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88337-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).

Predict Reactivity

Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-PPESNPDPVHSE, from the C Terminus of the protein sequence according to NP_000812.2; NP_001135741.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Gamma-Glutamyl Carboxylase,Vkcfd1,Ggcx

Background

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2008]

Database

DATA IMAGES
GTX88337_979_IHC-P_18121411_472.jpg

GTX88337 IHC-P Image

IHC-P analysis of human kidney using GTX88337 GGCX antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5µg/ml

GTX88337_2372_WB_18121411_107.jpg

GTX88337 WB Image

WB analysis of human muscle lysate using GTX88337 GGCX antibody, C-term.
Dilution : 0.3µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329