GeneTex
United States (US)

GGPS1 antibody

GTX106493_40744_IHC_19011506_163.jpg
GTX106493_40744_WB_19011506_193.jpg

Cat No. GTX106493

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:5000-1:20000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Positive Control

PC-3 , SK-N-SH

Predict Reactivity

Mouse, Rat, Zebrafish, Bovine, Xenopus laevis, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.9mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human GGPS1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GGPPS antibody, GGPPS1 antibody, GGPS1 antibody, GGPP synthase antibody, GGPPSase antibody, geranyltranstransferase antibody, "(2E,6E)-farnesyl diphosphate synthase antibody", farnesyltranstransferase antibody, dimethylallyltranstransferase antibody, geranylgeranyl pyrophosphate synthase antibody, farnesyl diphosphate synthase antibody, geranylgeranyl diphosphate synthase 1 antibody

Cellular Localization

Cytoplasm

Background

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Database

DATA IMAGES
GTX106493_40744_IHC_19011506_163.jpg

GTX106493 IHC-P Image

GGPS1 antibody detects GGPS1 protein at cytosol on BT483 xenograft by immunohistochemical analysis.
Sample: Paraffin-embedded BT483 xenograft.
GGPS1 antibody (GTX106493) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX106493_40744_WB_19011506_193.jpg

GTX106493 WB Image

Sample (30 ug of whole cell lysate)
A: PC-3
B: SK-N-SH
10% SDS PAGE
GTX106493 diluted at 1:10000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169