APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
5 - 7.5 μg/ml |
Assay dependent |
Not tested in other applications.
Predict Reactivity
Mouse, Rat, Monkey, Gibbon, Gorilla, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 13 amino acid peptide from N-terminal extracellular domain of human Ghrelin Receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375974
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
, GHDP , GHSR , growth hormone secretagogue receptor , Ghrelin Receptor , GHS-R1
Cellular Localization
Cell membrane
Background
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010]
Database
Research Area
DATA IMAGES
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GTX71871 IHC-P Image
IHC-P analysis of adrenal gland tissue using GTX71871 GHS-R1 antibody.
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GTX71871 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX71871 GHS-R1 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71871 IHC-P Image
IHC-P analysis of human pituitary, anterior tissue using GTX71871 GHS-R1 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71871 IHC-P Image
IHC-P analysis of brain, pituitary tissue using GTX71871 GHS-R1 antibody.
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REFERENCE
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REVIEW
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