APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
293T , human heart , human liver , MCF-7
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to an Internal region of Human GJC2
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
gap junction protein gamma 2 , CX46.6 , Cx47 , GJA12 , HLD2 , LMPH1C , LMPHM3 , PMLDAR , SPG44
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX47484 WB Image
WB analysis of MCF-7 cells using GTX47484 GJC2 antibody at 0.2-1μg/ml.
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GTX47484 IHC-P Image
IHC-P analysis of human heart tissue using GTX47484 GJC2 antibody at 1:100. Left to right:DAPI, GJC2, Merge. The low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.
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GTX47484 WB Image
WB analysis of human heart tissue using GTX47484 GJC2 antibody at 1μg/ml.
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GTX47484 WB Image
WB analysis of 293T cells using GTX47484 GJC2 antibody at 1μg/ml.
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GTX47484 WB Image
WB analysis of human liver tissue using GTX47484 GJC2 antibody at 1μg/ml.
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REFERENCE
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REVIEW
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