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GLIS2 antibody

Anti-GLIS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32148
Anti-GLIS2 antibody used in Western Blot (WB). GTX32148

Cat No. GTX32148

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

Positive Control

K562 Cell Lysate(GTX27911)

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.The immunogen is located within amino acids 260 - 310 of GLIS2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

GLIS family zinc finger 2 , NKL , NPHP7

Cellular Localization

Nucleus speckle,Cytoplasm

Background

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]

Database

DATA IMAGES

Anti-GLIS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX32148

GTX32148 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32148 GLIS2 antibody.
Working concentration : 5 μg/ml

Anti-GLIS2 antibody used in Western Blot (WB). GTX32148

GTX32148 WB Image

WB analysis of K562 cell lysate using GTX32148 GLIS2 antibody.
Working concentration : 1 μg/ml

REFERENCE

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Package List Price ($)
$ 329