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GLP1R antibody [HL2297]

Recombinant antibody Comparison
Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352
Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352
Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352
Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352
Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

Cat. No. GTX638352

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2297

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all GLP1R products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

human pancreas,mouse pancreas,rat pancreas

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide of human GLP1R.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R

Cellular Localization

Cell membrane

Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Database

Research Area

DATA IMAGES

Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

GTX638352 IHC-P Image

Comparison

GLP1R antibody [HL2297] detects GLP1R protein at cell membrane and cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse pancreas.
GLP1R stained by GLP1R antibody [HL2297] (GTX638352) diluted at 1:2000 and competitor's antibody (ab218532) diluted at 1:2000.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

*Competitor's antibody is not affiliated with GeneTex and does not endorse this product.

Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

GTX638352 IHC-P Image

GLP1R antibody [HL2297] detects GLP1R protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded rat pancreas.
GLP1R stained by GLP1R antibody [HL2297] (GTX638352) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

GTX638352 IHC-P Image

GLP1R antibody [HL2297] detects GLP1R protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded mouse pancreas.
GLP1R stained by GLP1R antibody [HL2297] (GTX638352) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

GTX638352 IHC-P Image

GLP1R antibody [HL2297] detects GLP1R protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded human pancreas.
GLP1R stained by GLP1R antibody [HL2297] (GTX638352) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-GLP1R antibody [HL2297] used in IHC (Paraffin sections) (IHC-P). GTX638352

GTX638352 IHC-P Image

GLP1R antibody [HL2297] detects GLP1R protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded mouse pancreas.
GLP1R stained by GLP1R antibody [HL2297] (GTX638352) diluted at 1:20000.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations