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GLP1R antibody

Anti-GLP1R antibody used in IHC (Paraffin sections) (IHC-P). GTX44806

Cat No. GTX44806

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 6 μg/ml
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Sheep, Bovine, Dog, Hamster, Chicken, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Panda, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GLP1R.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R

Cellular Localization

Cell membrane

Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Database

Research Area

DATA IMAGES

Anti-GLP1R antibody used in IHC (Paraffin sections) (IHC-P). GTX44806

GTX44806 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX44806 GLP1R antibody.
Antigen retrival : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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Package List Price ($)
$ 319