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GM-CSF Receptor alpha antibody

Anti-GM-CSF Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX37684
Anti-GM-CSF Receptor alpha antibody used in IHC (Frozen sections) (IHC-Fr). GTX37684
Anti-GM-CSF Receptor alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX37684

Cat No. GTX37684

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
100 μg ($409)
See all GM-CSF Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:100-500
IHC-P 1:400-800
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 111-220 amino acids of human CD116

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11170993

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

colony stimulating factor 2 receptor alpha subunit , CD116 , CDw116 , CSF2R , CSF2RAX , CSF2RAY , CSF2RX , CSF2RY , GM-CSF-R-alpha , GMCSFR , GMR , SMDP4 , alphaGMR

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GM-CSF Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX37684

GTX37684 IHC-P Image

IHC-P analysis of mouse intestine tissue using GTX37684 GM-CSF Receptor alpha antibody.
Fixation : 4% PFA
Antigen retireval : boiling with citrate buffer

Anti-GM-CSF Receptor alpha antibody used in IHC (Frozen sections) (IHC-Fr). GTX37684

GTX37684 IHC-Fr Image

IHC-Fr analysis of human cancerous bone marrow cells using GTX37684 GM-CSF Receptor alpha antibody.

Anti-GM-CSF Receptor alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX37684

GTX37684 ICC/IF Image

ICC/IF analysis of human cancerous bone marrow cells using GTX37684 GM-CSF Receptor alpha antibody.
Dilution : 1:350

REFERENCE

Application Reference

Katz S et al. Inflamm Res 2016; (Epub) GM-CSF and GM-CSF receptor have regulatory role in transforming rat mesenteric mesothelial cells into macrophage-like cells.
Application : IHC-Fr
Reactivity : Rat
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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 409