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GP2 antibody [GP2/1712]

Anti-GP2 antibody [GP2/1712] used in Western Blot (WB). GTX34766
Anti-GP2 antibody [GP2/1712] used in IHC (Paraffin sections) (IHC-P). GTX34766
Anti-GP2 antibody [GP2/1712] used in Protein Array (Protein Array). GTX34766

Cat No. GTX34766

Host

Mouse

Clonality

Monoclonal

Clone Name

GP2/1712

Isotype

IgG2b

Application

WB, IHC-P, ELISA, Protein Array

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).

Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Specificity/Sensitivity

We do not recommend use of this product for Mouse.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

GP2 , ZAP75 , glycoprotein 2

Cellular Localization

Cell membrane,Secreted

Background

This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-GP2 antibody [GP2/1712] used in Western Blot (WB). GTX34766

GTX34766 WB Image

WB analysis of human pancreas tissue lysate using GTX34766 GP2 antibody [GP2/1712].

Anti-GP2 antibody [GP2/1712] used in IHC (Paraffin sections) (IHC-P). GTX34766

GTX34766 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX34766 GP2 antibody [GP2/1712].

Anti-GP2 antibody [GP2/1712] used in Protein Array (Protein Array). GTX34766

GTX34766 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using GP2 Mouse Monoclonal Antibody (GP2/1712). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339