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GPNMB antibody [7C10E5]

Anti-GPNMB antibody [7C10E5] used in ELISA (ELISA). GTX60790
Anti-GPNMB antibody [7C10E5] used in IHC (Paraffin sections) (IHC-P). GTX60790
Anti-GPNMB antibody [7C10E5] used in Western Blot (WB). GTX60790
Anti-GPNMB antibody [7C10E5] used in Western Blot (WB). GTX60790
Anti-GPNMB antibody [7C10E5] used in IHC (Paraffin sections) (IHC-P). GTX60790

Cat No. GTX60790

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7C10E5

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($339)
See all GPNMB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glycoprotein nmb , HGFIN , NMB , PLCA3

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GPNMB antibody [7C10E5] used in ELISA (ELISA). GTX60790

GTX60790 ELISA Image

ELISA analysis of antigen using GTX60790 GPNMB antibody [7C10E5].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-GPNMB antibody [7C10E5] used in IHC (Paraffin sections) (IHC-P). GTX60790

GTX60790 IHC-P Image

IHC-P analysis of breast cancer tissue using GTX60790 GPNMB antibody [7C10E5].

Anti-GPNMB antibody [7C10E5] used in Western Blot (WB). GTX60790

GTX60790 WB Image

WB analysis of PANC1 (1) and PC-3 (2) cell lysate using GTX60790 GPNMB antibody [7C10E5].

Anti-GPNMB antibody [7C10E5] used in Western Blot (WB). GTX60790

GTX60790 WB Image

WB analysis of HEK293 (1) and GPNMB (AA: 31-260)-hIgGFc transfected HEK293 (2) cell lysate using GTX60790 GPNMB antibody [7C10E5].

Anti-GPNMB antibody [7C10E5] used in IHC (Paraffin sections) (IHC-P). GTX60790

GTX60790 IHC-P Image

IHC-P analysis of esophagus cancer tissue using GTX60790 GPNMB antibody [7C10E5].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339