For WB: Use at a dilution of 1:500-1:2,000. Optimal dilutions/concentrations should be determined by the researcher.
Jurkat whole cell lysate, A549 whole cell lysate.
Phosphate-buffered saline, pH 7.4, containing 0.02% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.5mg/ml(Please refer to the vial label for the specific concentration.)
Synthetic Peptide - amino acids 13-28 of human GPR15. The sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid
Affinity purified with antigen
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
GPR15, 2838, P49685, 601166, MGC126828, MGC126830
Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G -protein coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 andV28 were recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G-protein-coupled receptor 15 and brother of Bonzo, respectively,) were recently cloned (1,2). This novel G protein-coupled receptor serves as co-receptor for simian immunodeficiency virus (SIV), and for strains of HIV-2and M-tropic HIV-1 (2,3). The ligand for GPR15 has not been identified yet.
GTX28104 WB Image
Western blot analysis of GPR15 in human heart lysate with anti- GPR15 (NT) in the absence (lane 1) or presence of specific peptide (lane 2) or non related peptide (lane 3)