GeneTex
United States (US)

GPR15 antibody

GPR15-antibody-GTX28104-WB-1_18121410_285.jpg

Cat No. GTX28104

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

For WB: Use at a dilution of 1:500-1:2,000. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

41 kDa. ( Note )

Positive Control

Jurkat whole cell lysate, A549 whole cell lysate.
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic Peptide - amino acids 13-28 of human GPR15. The sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid

Purification

Affinity purified with antigen

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GPR15, 2838, P49685, 601166, MGC126828, MGC126830

Background

Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G -protein coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 andV28 were recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G-protein-coupled receptor 15 and brother of Bonzo, respectively,) were recently cloned (1,2). This novel G protein-coupled receptor serves as co-receptor for simian immunodeficiency virus (SIV), and for strains of HIV-2and M-tropic HIV-1 (2,3). The ligand for GPR15 has not been identified yet.

Database

DATA IMAGES
GPR15-antibody-GTX28104-WB-1_18121410_285.jpg

GTX28104 WB Image

Western blot analysis of GPR15 in human heart lysate with anti- GPR15 (NT) in the absence (lane 1) or presence of specific peptide (lane 2) or non related peptide (lane 3)

Package List Price ($)
$ 329