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GPR15 peptide

Cat. No. GTX26101

Application

Neutralizing/Inhibition

Species

Human
Package
50 μg ($139)

APPLICATION

Application Note

The peptide is used for blocking the activity of anti-GPR15 (cat. no GTX28104). Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks the antibody activity in Western blotting.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

G Protein-Coupled Receptor 15 , Bob , Gpr15

Background

Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein coupled receptors, including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively) were recently cloned. This novel G protein coupled receptor serves as co-receptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139