APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
12 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Bat, Elephant, Gorilla, Horse, Marmoset, Opossum, Panda, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR153.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
G protein-coupled receptor 153 , G proteincoupled receptor 153 , GPR153 , PGR1
Cellular Localization
Cell membrane
Background
This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017]
Database
Research Area
DATA IMAGES
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GTX12615 IHC-P Image
IHC-P analysis of human pancreas, carcinoma tissue using GTX12615 GPR153 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX12615 IHC-P Image
IHC-P analysis of human breast, carcinoma tissue using GTX12615 GPR153 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX12615 IHC-P Image
IHC-P analysis of human liver, hepatocytes tissue using GTX12615 GPR153 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX12615 IHC-P Image
IHC-P analysis of brain, medulla, hypoglossal nucleus tissue using GTX12615 GPR153 antibody.
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GTX12615 IHC-P Image
IHC-P analysis of ovary, carcinoma tissue using GTX12615 GPR153 antibody.
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REFERENCE
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REVIEW
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