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GPR30 antibody

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564
Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564
Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564
Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564
Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564
Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

Cat No. GTX12564

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 41 - 62 μg/ml
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Zebrafish, Rabbit, Bovine, Dog, Hamster, Chicken, Monkey, Bat, Elephant, Gorilla, Horse, Marmoset, Opossum, Panda, Pufferfish, Turkey, Xenopus, Platypus, Sea bass, Stickleback, Zebra finch(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR30.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

G protein-coupled estrogen receptor 1 , CEPR , CMKRL2 , DRY12 , FEG1 , G proteincoupled estrogen receptor 1 , GPCRBr , GPER , GPER1 , GPR30 , LERGU , LERGU2 , LyGPR , mER

Cellular Localization

Nucleus,Cytoplasm,Perinuclear region,Cytoskeleton,Cell membrane,Basolateral cell membrane,Cytoplasmic vesicle membrane,Early endosome,Recycling endosome,Golgi apparatus membrane,Golgi apparatus,trans-Golgi network,Endoplasmic reticulum membrane,Cell projection,Dendrite,Dendritic spine membrane,Axon,Cell junction,Synapse,Postsynaptic cell membrane,Postsynaptic density,Mitochondrion membrane

Background

This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of lung, non small cell carcinoma tissue using GTX12564 GPR30 antibody.

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of prostate, adenocarcinoma tissue using GTX12564 GPR30 antibody.

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of human colon, carcinoma tissue using GTX12564 GPR30 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of human colon, carcinoma tissue using GTX12564 GPR30 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX12564 GPR30 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-GPR30 antibody used in IHC (Paraffin sections) (IHC-P). GTX12564

GTX12564 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX12564 GPR30 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339