*Optimal dilutions/concentrations should be determined by the researcher.
|41 - 62 μg/ml
Not tested in other applications.
Mouse, Rat, Zebrafish, Rabbit, Bovine, Dog, Hamster, Chicken, Monkey, Bat, Elephant, Gorilla, Horse, Marmoset, Opossum, Panda, Pufferfish, Turkey, Xenopus, Platypus, Sea bass, Stickleback, Zebra finch(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR30.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
G protein-coupled estrogen receptor 1 , CEPR , CMKRL2 , DRY12 , FEG1 , G proteincoupled estrogen receptor 1 , GPCRBr , GPER , GPER1 , GPR30 , LERGU , LERGU2 , LyGPR , mER
Nucleus,Cytoplasm,Perinuclear region,Cytoskeleton,Cell membrane,Basolateral cell membrane,Cytoplasmic vesicle membrane,Early endosome,Recycling endosome,Golgi apparatus membrane,Golgi apparatus,trans-Golgi network,Endoplasmic reticulum membrane,Cell projection,Dendrite,Dendritic spine membrane,Axon,Cell junction,Synapse,Postsynaptic cell membrane,Postsynaptic density,Mitochondrion membrane
This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]