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GPR44 antibody

Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573
Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573
Anti-GPR44 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX12573
Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573

Cat No. GTX12573

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P

Reactivity

Human, Monkey
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P 16 - 32 μg/ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Rabbit, Bovine, Dog, Guinea pig, Pig, Elephant, Gibbon, Gorilla, Horse, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from 3rd extracellular domain of human GPR44 / CRTH2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

prostaglandin D2 receptor 2 , CD294 , CRTH2 , DL1R , DP2 , GPR44 , PTGDR2 , TLR10

Cellular Localization

Cell membrane

Background

This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573

GTX12573 IHC-P Image

IHC-P analysis of brain, alzheimer's disease senile plaque tissue using GTX12573 GPR44 antibody.

Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573

GTX12573 IHC-P Image

IHC-P analysis of brain, amygdala tissue using GTX12573 GPR44 antibody.

Anti-GPR44 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX12573

GTX12573 ICC/IF Image

ICC/IF analysis of HEK293 transfected with GPR44 using GTX12573 GPR44 antibody.

Anti-GPR44 antibody used in IHC (Paraffin sections) (IHC-P). GTX12573

GTX12573 IHC-P Image

IHC-P analysis of human nasal mucosa, eosinophils tissue using GTX12573 GPR44 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf