APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Jurkat Cell Lysate(GTX27899) , Human Heart Tissue Lysate(GTX27916) , Human Heart Tissue Slide
Product Note
At least two different isoforms are known to exist; this antibody will detect both isoforms.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
GPR44 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human GPR44.The immunogen is located within the first 50 amino acids of GPR44.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
prostaglandin D2 receptor 2 , CD294 , CRTH2 , DL1R , DP2 , GPR44
Cellular Localization
Cell membrane
Background
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
Database
Research Area
DATA IMAGES
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GTX31303 IHC-P Image
IHC-P analysis of human heart tissue using GTX31303 GPR44 antibody. Working concentration : 2.5 μg/ml
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GTX31303 IHC-P Image
IHC-P analysis of human heart tissue using GTX31303 GPR44 antibody. Working concentration : 20 μg/ml
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GTX31303 WB Image
WB analysis of Jurkat cell lysate in (A) the absence and (B) presence of blocking peptide using GTX31303 GPR44 antibody. Working concentration : 1 μg/ml
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REFERENCE
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REVIEW
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