Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Reacts with residues 329-348 [DDSELGGAGSSRRRRTSSTA] of the CRTH2 (GPR44) protein. This sequence is near the C terminus. Cross reacts with rat and mouse.
PBS containing 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Affinity purified IgG
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Prostaglandin D2 Receptor 2 , Cd294 , Crth2 , Dl1R , Dp2 , Gpr44 , Ptgdr2
CRTH2 (chemoattractant receptor-homologous molecule), which is also known as the putative G protein-coupled receptor (GPR44), is expressed on Th2 cells and is a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells. CRTH2 is selectively expressed in vivo in an activated state of Th2 cells including allergen-responsive Th2 cells, suggesting its pivotal roles in ongoing Th2-type immune reactions.
GTX70387 WB Image
Western blot analysis of CRTH2 in CRTH2-transfected Jurkat cell lysate. Does not detect CRTH2 in non-transfected parental Jurkat cells.