APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
5 - 10 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rabbit, Bovine, Dog, Pig, Monkey, Gibbon, Gorilla(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 33 amino acid peptide from N-terminal extracellular domain of human GPR44 / CRTH2.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_371197
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
prostaglandin D2 receptor 2 , CD294 , CRTH2 , DL1R , DP2 , GPR44 , PTGDR2 , TLR10
Cellular Localization
Cell membrane
Background
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
Database
Research Area
DATA IMAGES
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GTX71385 IHC-P Image
IHC-P analysis of lung, small cell carcinoma tissue using GTX71385 GPR44 antibody.
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GTX71385 IHC-P Image
IHC-P analysis of human nasal mucosa, eosinophils tissue using GTX71385 GPR44 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71385 IHC-P Image
IHC-P analysis of human lymph node, non-hodgkins lymphoma tissue using GTX71385 GPR44 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71385 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX71385 GPR44 antibody.
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GTX71385 IHC-P Image
IHC-P analysis of brain, thalamus, neuron tissue using GTX71385 GPR44 antibody.
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GTX71385 ICC/IF Image
ICC/IF analysis of HEK293 transfected with GPR44 using GTX71385 GPR44 antibody.
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REFERENCE
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REVIEW
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